Publications

Dinitrogen Binding and Activation at a Molybdenum–Iron–Sulfur Cluster
McSkimming, A.; Suess, D. L. M.; Nat. Chem. (2021), in press.

 

A Terminal Imido Complex of an Iron–Sulfur Cluster
Sridharan, A.; Brown, A.C.; Suess, D. L. M.; Angew. Chem. Int. Ed. (2021), in press, DOI: 10.1002/anie.202102603.

[Paper (PDF)] [Supporting Information (PDF)]

 

Synthetic Iron–Sulfur Clusters
Brown, A.C.; Suess, D. L. M.; in Comprehensive Coordination Chemistry 3 (2021), in press, DOI: 10.1016/B978-0-08-102688-5.00053-2.

 

Postbiosynthetic Modification of a Precursor to the Nitrogenase Iron–Molybdenum Cofactor
Srisantitham, S.; Badding, E. D; Suess, D. L. M. Proc. Natl. Acad. Sci. U.S.A. 118, e2015361118 (2021), DOI: 10.1021/pnas.2015361118.

[Paper (PDF)] [Supporting Information (PDF)]

 

Reversible Formation of Alkyl Radicals at [Fe4S4] Clusters and its Implications for Selectivity in Radical SAM Enzymes
Brown, A. C.; Suess, D. L. M. J. Am. Chem. Soc. 142, 14240–14248 (2020), DOI: 10.1021/jacs.0c05590.

[Paper (PDF)] [Supporting Information (PDF)]

 

An [Fe4S4]3+–Alkyl Cluster Stabilized by an Expanded Scorpionate Ligand
McSkimming, A.; Sridharan, A.; Thompson, N. B.; Müller, P.; Suess, D. L. M. J. Am. Chem. Soc. 142, 14314–14323 (2020), DOI: 10.1021/jacs.0c06334.

[Paper (PDF)] [Supporting Information (PDF)]

 

A Synthetic Model of Enzymatic [Fe4S4]–Alkyl Intermediates
Ye, M.; Thompson, N. B.; Brown, A. C.; Suess, D. L. M. J. Am. Chem. Soc. 141, 13330–13335 (2019), DOI: 10.1021/jacs.9b06975.

[Paper (PDF)] [Supporting Information (PDF)]

 

Controlling Substrate Binding to Fe4S4 Clusters Through Remote Steric Effects
Brown, A. C.; Suess, D. L. M. Inorg. Chem. 58, 5273–5280 (2019), DOI: 10.1021/acs.inorgchem.9b00360.

[Paper (PDF)] [Supporting Information (PDF)]

 

Selective Synthesis of Site-Differentiated Fe4S4 and Fe6S6 Clusters
McSkimming, A.; Suess, D. L. M. Inorg. Chem. 57, 14904–14912 (2018), DOI: 10.1021/acs.inorgchem.8b02684.

[Paper (PDF)] [Supporting Information (PDF)]

 

Publications from undergraduate, graduate, and postdoctoral studies
 

Rao, G.; Tau, L.; Suess, D. L. M.; Britt, R. D. A [4Fe–4S]-Fe(CO)(CN)-L-cysteine intermediate is the first organometallic precursor in [FeFe] hydrogenase H-cluster bioassembly. Nat. Chem. 10, 555–560 (2018), DOI: 10.1038/s41557-018-0026-7.

Guo, Y.; Suess, D. L. M.; Herzik, M. A.; Iavarone, A. T.; Britt, R. D.; Marletta, M. A. Regulation of nitric oxide signaling by formation of a distal receptor–ligand complex. Nat. Chem. Biol. 13, 1216–1221 (2017), DOI: 10.1038/nchembio.2488.

Nguyen, A. I.; Suess, D. L. M.; Darago, L. E.; Oyala, P. H.; Levine, D. S.; Ziegler, M. S.; Britt, R. D.; Tilley, T. D. Manganese–Cobalt Oxido Cubanes Relevant to Manganese-Doped Water Oxidation Catalysts. J. Am. Chem. Soc. 139, 5579–5587 (2017), DOI: 10.1021/jacs.7b01792.

Span, E. A.; Suess, D. L. M.; Deller, M. C.; Britt, R. D.; Marletta, M. A. The Role of the Secondary Coordination Sphere in a Fungal Polysaccharide Monooxygenase. ACS Chem. Biol. 12, 1095–1103 (2017), DOI: 10.1021/acschembio.7b00016.

Suess, D. L. M.; Pham, C. C.; Bürstel, I.; Swartz, J. R.; Cramer, S. P.; Britt, R. D. The Radical SAM Enzyme HydG Requires Cysteine and a Dangler Iron for Generating an Organometallic Precursor to the [FeFe]-Hydrogenase H-Cluster. J. Am. Chem. Soc. 138, 1146–1149 (2016), DOI: 10.1021/jacs.5b12512.

Suess, D. L. M.; Kuchenreuther, J. M.; De La Paz, L.; Swartz, J. R.; Britt, R. D. Biosynthesis of the [FeFe] Hydrogenase H Cluster: A Central Role for the Radical SAM Enzyme HydG. Inorg. Chem. 55, 478–487 (2016), DOI: 10.1021/acs.inorgchem.5b02274.

Richardson, D. P.; Bauer, G. S.; Bravo, A. A.; Drzyzga, M.; Motazedi, T.; Pelegri-O’Day, E. M.; Poudyal, S.; Suess, D. L. M.; Thoman, J. W. A convenient and practical method for the selective preparation of deuterofluorocarbons. J. Fluor. Chem. 180, 208–215 (2015), DOI: 10.1016/j.jfluchem.2015.10.002.

Nesbit, M. A.; Suess, D. L. M.; Peters, J. C. E–H Bond Activations and Hydrosilylation Catalysis with Iron and Cobalt Metalloboranes. Organometallics 34, 4741–4752 (2015), DOI: 10.1021/acs.organomet.5b00530.

Del Castillo, T. J.; Thompson, N. B.; Suess, D. L. M.; Ung, G.; Peters, J. C. Evaluating Molecular Cobalt Complexes for the Conversion of N2 to NH3. Inorg. Chem. 54, 9256–9262 (2015), DOI: 10.1021/acs.inorgchem.5b00645.

Suess, D. L. M.; Bürstel, I.; De La Paz, L.; Kuchenreuther, J. M.; Pham, C. C.; Cramer, S. P.; Swartz, J. R.; Britt, R. D. Cysteine as a ligand platform in the biosynthesis of the FeFe hydrogenase H cluster. Proc. Natl. Acad. Sci. 112, 11455–11460 (2015), DOI: 10.1073/pnas.1508440112.

Suess, D. L. M.; Britt, R. D. EPR Spectroscopic Studies of [FeFe]-Hydrogenase Maturation. Top. Catal. 58, 699–707 (2015), DOI: 10.1007/s11244-015-0412-y.

Britt, R. D.; Suess, D. L. M.; Stich, T. A. An Mn(V)-oxo role in splitting water? Proc. Natl. Acad. Sci. 112, 5265–5266 (2015), DOI: 10.1073/pnas.1505223112.

Dinis, P.; Suess, D. L. M.; Fox, S. J.; Harmer, J. E.; Driesener, R. C.; De La Paz, L.; Swartz, J. R.; Essex, J. W.; Britt, R. D.; Roach, P. L. X-ray crystallographic and EPR spectroscopic analysis of HydG, a maturase in [FeFe]-hydrogenase H-cluster assembly. Proc. Natl. Acad. Sci. 112, 1362–1367 (2015), DOI: 10.1073/pnas.1417252112.

Gunderson, W. A.; Suess, D. L. M.; Fong, H.; Wang, X.; Hoffmann, C. M.; Cutsail III, G. E.; Peters, J. C.; Hoffman, B. M. Free H2 Rotation vs. Jahn–Teller Constraints in the Nonclassical Trigonal (TPB)Co–H2 Complex. J. Am. Chem. Soc. 136, 14998–15009 (2014), DOI: 10.1021/ja508117h.

Myers, W. K.; Stich, T. A.; Suess, D. L. M.; Kuchenreuther, J. M.; Swartz, J. R.; Britt, R. D. The Cyanide Ligands of [FeFe] Hydrogenase: Pulse EPR Studies of 13C and 15N-Labeled H-Cluster. J. Am. Chem. Soc. 136, 12237–12240 (2014), DOI: 10.1021/ja507046w.

Kuchenreuther, J. M.; Myers, W. K.; Suess, D. L. M.; Stich, T. A.; Pelmenschikov, V.; Shiigi, S. A.; Cramer, S. P.; Swartz, J. R.; Britt, R. D.; George, S. J. The HydG enzyme generates an Fe(CO)2(CN) synthon in assembly of the FeFe hydrogenase H-cluster. Science 343, 424–427 (2014), DOI: 10.1126/science.1246572.

Suess, D. L. M.; Peters, J. C. A CO-Derived Iron Dicarbyne That Releases Olefin upon Hydrogenation. J. Am. Chem. Soc. 135, 12580–12583 (2013), DOI: 10.1021/ja406874k.

Suess, D. L. M.; Peters, J. C. H–H and Si–H Bond Addition to Fe≡NNR2 Intermediates Derived from N2. J. Am. Chem. Soc. 135, 4938–4941 (2013), DOI: 10.1021/ja400836u.

Suess, D. L. M.; Tsay, C.; Peters, J. C. Dihydrogen Binding to Isostructural S = ½ and S = 0 Cobalt Complexes. J. Am. Chem. Soc. 134, 14158–14164 (2012), DOI: 10.1021/ja305248f.

Suess, D. L. M.; Peters, J. C. Late-Metal Diphosphinosulfinyl S(O)P2 Pincer-type Complexes. Organometallics 31, 5213–5222 (2012), DOI: 10.1021/om3001229.

Suess, D. L. M.; Peters, J. C. Ligand design for site-selective installation of Pd and Pt centers to generate homo- and heteropolymetallic motifs. Chem. Commun. 46, 6554–6556 (2010), DOI: 10.1039/c003163a.